According to the label From the product label

These details were extracted from this product's label PDF. The label is the law. Confirm every rate, site, restriction and safety requirement against the label before mixing or applying. Check for a state supplemental label; a product may be restricted or prohibited in a state or site even when a rate appears below. · EPA registration data for Reg. 100-1268 →

Prefix Herbicide is a selective herbicide formulated as an emulsifiable concentrate (EC) used for the control or partial control of certain grass, broadleaf, and sedge weeds. It is specifically designed for use in soybeans and cotton. The active ingredients are S-metolachlor (46.4%) and Sodium Salt of Fomesafen (10.2%). It can be applied as a preplant surface, preplant incorporated, preemergence, or postemergence treatment in soybeans and cotton, as well as a post-directed treatment in cotton. When handling, users must wear personal protective equipment including long-sleeved shirts, long pants, chemical-resistant gloves (barrier laminate ≥ 14 mils or Viton™ ≥ 14 mils), plus socks, and protective eyewear (goggles, face shield, or safety glasses). Avoid application during temperature inversions or when wind speeds exceed 15 mph. The product is known to leach through soil into groundwater, so use caution in areas with permeable soils or shallow water tables. Note: Sale, use, and distribution is prohibited in Nassau and Suffolk Counties, New York.

Pests covered (2)

certain grasses, broadleaf, and sedge weedsBroadleaf Weeds, Grasses

Areas treatable (1)

soybeans and cotton

Application instructions from the label 1

soybeans and cotton

Can be applied as preplant surface, preplant incorporated, preemergence, or postemergence in soybeans and cotton; post-directed in cotton.

Target pest: certain grasses, broadleaf, and sedge weeds
Location: Both

Worker safety

Re-entry interval (REI) 24

PPE required Long-sleeved shirt and long pants; Chemical-resistant gloves made of barrier laminate ≥ 14 mils or Viton™ ≥ 14 mils; Shoes plus socks; Protective eyewear (goggles, face shield, or safety glasses).

Timing & weather

Do not apply when wind speeds exceed 15 mph.
Do not apply during temperature inversions.

Use restrictions 4

Sale, use, and distribution is prohibited in Nassau and Suffolk Counties in the State of New York.
Do not apply directly to water or areas where surface water is present or to intertidal areas below the mean high water mark.
Do not apply when weather conditions favor drift from target area.
Do not apply during temperature inversions.

Catalog source document available. The local copy is still withheld until its exact product identity, role, and full file hash are accepted. Open the catalog source label ↗ and verify the product name, EPA registration number, and revision before relying on it.

Publication withheld. This catalog record has no active evidence summary, so its document and any extracted directions remain unavailable while identity and document role are reviewed.

Document text and citations

Extracted text is retained internally for document review and page-level citation checks. The complete third-party text is not republished here; use the document viewer above.

Reference only. Always read and follow the most current EPA-approved label on the product container. State and local restrictions may apply that are not reflected in this digitised copy. Verify the EPA registration number and revision date before use.