Madex XLV

Certis · Cydia pomonella granulovirus isolate GV-0017 0.06% · EPA Reg 69553-12-70051 · Insecticide ✓ Last verified 2026-05-30

Free practice questions on this product's label, use, and safety.

Key facts From the EPA

Registration, signal word, restricted-use status and approved use sites are sourced from the U.S. EPA pesticide registry. EPA Reg. No. 69553-12-70051. EPA pesticide labels ↗

Active ingredient Cydia pomonella granulovirus isolate GV-0017 0.06%

Manufacturer Certis

EPA registration 69553-12-70051

Category Insecticide

Target pests Moths

According to the label From the product label

These application details were read from this product's label by our system to help you in the field. The label is the law — always confirm rates, sites and restrictions against the actual product label before mixing or applying. View the full label →

Madex XLV is a biological insecticide containing the insecticidal virus Cydia pomonella granulovirus isolate GV-0017 (0.06%). It is specifically designed for organic production to control the larvae of the Codling Moth and the Oriental Fruit Moth. The product works by being ingested by the larvae, where the viral occlusion bodies (OBs) dissolve and release infectious virions that replicate within the insect, eventually causing death. It is used as a spray on fruit and foliage of trees, including apple, pear, quince, apricot, peach, plum, cherry, nectarine, and various nut trees. For effective control, thorough spray coverage of target foliage and fruit is essential. The product is fast-acting once ingested, though mortality occurs a few days after ingestion. When handling, avoid contact with eyes and skin; if contact occurs, rinse thoroughly with water. Use appropriate personal protective equipment, including long-sleeved shirts, long pants, waterproof gloves, shoes plus socks, and protective eyewear. Note that the product breaks down under direct sunlight, so timing and coverage are critical for efficacy.

Application rates & sites 1

Target pest	Indoor / Outdoor	Where on site	Rate	Dilution	Infestation level	Notes
Codling Moth larvae, Oriental Fruit Moth larvae	Outdoor	Fruit and foliage of trees (including apple, pear, quince, apricot, peach, plum, cherry, nectarine, and nut trees)	0.5 - 3.0 fluid ounces per acre fl oz/acre	Mix with water at or near neutral pH (7)		Target small larvae early in their life cycle. Make at least 2 and up to 6 applications per moth larval generation.

Mixing & dilution 1

For	Where	Amount	Per	Finished strength	Notes
Codling Moth and Oriental Fruit Moth		0.5 - 3.0	fl oz	per acre	Use water at or near neutral pH (7). Select spray volume appropriate to tree size and density (50-100 gallons for small trees; 100-200 gallons for larger trees with denser canopies).

PPE required Long-sleeved shirt and long pants; waterproof gloves; shoes plus socks; protective eyewear.

Timing & weather

Apply early in the larval life cycle. Reapply after 6-8 sunny days (counting 2 partially sunny days as 1 sunny day) if moths are still flying and laying eggs.
Product breaks down under direct sunlight.

Use restrictions 2

Do not apply directly to water or areas where surface water is present or to intertidal areas below the mean high-water mark. Do not apply through any type of irrigation.
May be applied up to and including the day of harvest.

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